PODCAST

Rewired: The Ibogaine Experience

By Sarah Mitchell

About This Podcast

Welcome to ‘Rewired: The Ibogaine Experience,’ an intimate journey into lives transformed by ibogaine therapy. Join us for powerful conversations with patients, families, and practitioners from The Iboga Wellness Institute as they share real stories of healing. From veterans with PTSD to those overcoming addiction and Parkinson’s patients finding relief, discover the moments that led them to this treatment. Our podcast explores the intersection of research and recovery, revealing ibogaine’s potential for genuine transformation when conventional medicine falls short.

Explore All Episodes

Daisy serves as the Clinical Director at Iboga Wellness Institute, where she oversees the coordination of patient care, treatment preparation, and post-experience integration to ensure each individual receives comprehensive, compassionate, and medically aligned support throughout their healing journey. With a multidisciplinary background that combines clinical coordination, integrative wellness, and advanced nutritional practice, Daisy plays a central role in bridging medical treatment with sustainable lifestyle transformation.

As Clinical Director, Daisy manages the continuum of care from initial intake through post-treatment follow-up. She works closely with the medical team, led by Dr. Omar A. Calderón, to ensure that every client is properly prepared—physically, emotionally, and nutritionally—for ibogaine therapy. Her responsibilities include reviewing health histories, coordinating pre-treatment requirements, guiding clients through preparation protocols, and ensuring that each case is handled with precision, discretion, and individualized attention.

In her role as an Integration Specialist, Daisy helps clients translate their ibogaine experience into meaningful, lasting change. She provides structured pre-integration education and post-treatment support designed to help individuals process insights, stabilize routines, and build healthy behavioral patterns that reinforce neurological reset and emotional healing. Her approach emphasizes grounding, accountability, and practical application, allowing clients to return home with clear strategies for maintaining progress. Daisy understands that ibogaine is not a standalone solution, but rather a catalyst for transformation that must be supported through intentional integration and lifestyle alignment.

Daisy is also a highly experienced Nutritionist, specializing in therapeutic nutrition that supports neuroregulation, metabolic restoration, and overall physiological balance. She designs individualized nutritional plans that focus on replenishment, inflammation reduction, gut health optimization, and micronutrient support—critical elements for patients recovering from substance use, chronic stress, or neurological dysregulation. Her programs incorporate whole-food strategies, targeted supplementation guidance, and education on sustainable dietary habits that extend far beyond a client’s stay at the Institute.

Her philosophy centers on the understanding that true healing requires alignment of body, mind, and environment. By integrating clinical structure with holistic wellness principles, Daisy ensures that each client is not only medically safe during treatment but also empowered with the tools necessary to sustain long-term recovery and vitality.

Known for her meticulous organization, warm presence, and unwavering dedication to patient advocacy, Daisy has become a trusted guide for clients navigating some of the most pivotal moments of their lives. She brings both professionalism and empathy to every interaction, creating an atmosphere where individuals feel supported, informed, and confident in their path forward.

At The Iboga Wellness Institute, Daisy’s leadership helps define the standard of care—one that unites medical excellence, integrative support, and nutritional science to foster lasting transformation and whole-person wellness.

Ray Rodriguez serves as a Psychedelic Integration Coach and Recovery Mentor at Iboga Wellness Institute, bringing over a decade of direct, hands-on experience supporting individuals and families navigating addiction recovery, personal transformation, and long-term post-treatment integration. His work is grounded in both professional training and lived experience, allowing him to guide clients with authenticity, empathy, and practical insight.

Certified through Being True To You, Ray has worked extensively within family systems and recovery-oriented frameworks, helping clients prepare for treatment, navigate the depth of their therapeutic experience, and translate insights into meaningful, sustainable life changes. He spent five years working one-on-one within one of the first viable ibogaine therapeutic aftercare programs, where he provided structured reintegration support for individuals transitioning from clinical treatment back into everyday life. This experience shaped his specialization in stabilization, accountability, and long-term success beyond the acute treatment phase.

Ray’s personal journey includes recovery from opiate addiction, an experience that informs his compassionate, nonjudgmental approach. His own healing path led him to explore plant medicine as a catalyst for deeper change, and he has since supported individuals working with modalities including ibogaine, ayahuasca, kambo, and bufo. His philosophy prioritizes safety, preparation, and responsibility—emphasizing that true healing is not defined by peak experiences, but by the ability to integrate those experiences into lasting behavioral, emotional, and relational transformation.

Well-versed in multiple recovery models, Ray works fluidly within both 12-Step programs and SMART Recovery, meeting clients within their chosen framework without imposing ideology. His coaching style is collaborative and client-centered, honoring each individual’s worldview, belief system, and stage of readiness while providing grounded structure and accountability.

In addition to his integration and recovery work, Ray is a Certified Holographic Sound Practitioner, incorporating harmonic and sound-based modalities when appropriate to support nervous system regulation and emotional processing. His methodology weaves together embodiment practices, yoga, nature-based experiences, frequency work, and structured integration strategies designed to help clients anchor insights into daily living.

Areas of Specialization

Pre-ibogaine preparation and intention setting
Post-treatment integration and stabilization
Therapeutic aftercare and recovery support
Family systems education and alignment
Addiction recovery coaching and relapse prevention
Nervous system regulation and embodiment practices
Bridging traditional recovery models with psychedelic-assisted healing

At The Iboga Wellness Institute, Ray plays a vital role in ensuring that healing extends far beyond the clinical setting. His work focuses on helping individuals transform profound therapeutic experiences into sustainable, embodied change—supporting them as they rebuild lives rooted in clarity, resilience, and purpose.

Mike Powers is a Co-Founder of Iboga Wellness Institute, where he combines his personal journey of recovery with a strong background in business leadership and entrepreneurship to help guide the organization’s mission of delivering safe, innovative, and compassionate care. Mike’s path to this work is rooted in both extraordinary athletic achievement and firsthand experience with the long-term consequences of high-impact sports.

As a standout collegiate football player, Mike , earned the distinction of being a two-time national champion and receiving prestigious All-American honors. His athletic career was defined by discipline, perseverance, and an unrelenting commitment to performance—traits that later became essential as he faced the physical toll of the game. After sustaining multiple concussions, Mike began to experience the cumulative neurological effects associated with traumatic brain injury and, ultimately, Chronic Traumatic Encephalopathy (CTE). Like many former athletes, he encountered limited treatment options within conventional Western medicine that addressed symptoms but failed to offer meaningful restoration or healing.

Determined to find answers beyond traditional models of care, Mike began exploring alternative therapies. This search led him to ibogaine treatment, an experience that proved to be profoundly transformative. Through this process, Mike experienced significant improvements in clarity, emotional well-being, and overall quality of life—an outcome that reshaped not only his health, but also his sense of purpose. The experience ignited a deep commitment to helping others who were facing similar neurological, psychological, and substance-related challenges discover pathways to healing that had previously seemed out of reach.

Motivated by this mission, Mike co-founded Iboga Wellness Institute to create a medically responsible, ethically grounded environment where individuals could access ibogaine therapy within a structured framework that prioritizes safety, clinical oversight, and whole-person care. His vision has been instrumental in shaping the Institute’s focus on supporting individuals suffering from traumatic brain injuries, addiction, and other complex conditions through integrative, evidence-informed approaches.

In addition to his work in the health and wellness space, Mike is a seasoned American entrepreneur who has been a part of multiple businesses across diverse industries. This extensive business experience provides the operational foundation necessary to build sustainable treatment environments that meet rigorous professional standards.

Mike brings a unique combination of lived experience, executive leadership, and unwavering compassion to The Iboga Wellness Institute. His journey from elite athlete to advocate for innovative healing allows him to connect deeply with those seeking recovery and renewal. Through his work, Mike remains dedicated to expanding awareness, accessibility, and responsible delivery of ibogaine therapy offering hope to individuals and families searching for meaningful solutions beyond conventional care.

James Collins is the Co-Founder and Chief Executive Officer of Iboga Wellness Institute, where he has played an integral role in the vision, development, and operational launch of the organization. With a diverse entrepreneurial background and decades of experience owning and operating multiple businesses throughout the United States, James brings a unique blend of executive leadership, operational strategy, and client-centered service to the rapidly evolving field of ibogaine-assisted therapy.

Before co-founding Iboga Wellness Institute, James built a successful career across several industries, including real estate development , hospitality, sales, and business development. His extensive experience in launching, scaling, and managing companies has equipped him with the operational discipline and financial oversight necessary to build sustainable, compliant, and patient-focused wellness environments. His entrepreneurial track record reflects a consistent ability to transform vision into structured, results-driven organizations.

James also possesses a strong background in marketing and brand development, having led strategic initiatives that positioned businesses for growth in competitive markets. This expertise has been instrumental in shaping the identity and outreach of Iboga Wellness Institute, helping to elevate awareness of ibogaine therapy while maintaining a professional, ethical, and medically responsible presence.

Throughout his lengthy career in sales and customer service, James cultivated a deep understanding of client relationships and the importance of trust, transparency, and individualized care. These principles now guide the Institute’s patient experience model, ensuring that every individual who walks through the doors is treated with dignity, compassion, and the highest level of support.

Known for his dedication, integrity, and hands-on leadership style, James is deeply committed to advancing the responsible integration of plant-based medicines into modern therapeutic frameworks. He is a passionate advocate for the ibogaine movement, working to expand safe, structured access not only in Mexico but worldwide. His mission is to help bridge the gap between traditional healing knowledge and contemporary medical standards, creating pathways for individuals seeking recovery, neurological support, and personal transformation.

At the core of James’s work is a sincere belief in healing through compassion, structure, and innovation. His leadership continues to drive Iboga Wellness Institute’s growth as a center focused on safety, education, and meaningful outcomes for those seeking lasting change.

Neurological Conditions & Chronic Pain

Repair Mechanisms Medicine Considers Impossible

Conventional neurology treats most conditions as irreversible—managing symptoms while accepting inevitable decline. Ibogaine challenges that assumption by stimulating neurological repair processes that modern medicine barely understands.

Parkinson's Disease

Multiple clinical studies document significant tremor reduction following ibogaine treatment. Patients report improved motor control, reduced rigidity, better sleep, and cognitive clarity. The mechanism involves GDNF (glial cell line-derived neurotrophic factor) production—a protein that protects dopamine neurons and may slow disease progression.

Multiple Sclerosis

MS patients report reduced inflammation, improved mobility, decreased fatigue, and symptom stabilization. While not a cure, ibogaine appears to interrupt the neuroinflammatory cascade driving MS progression and potentially support remyelination.

Traumatic Brain Injury & Post-Concussion Syndrome

Veterans with blast exposure, athletes with multiple concussions, accident survivors with persistent TBI symptoms—patients given no hope for improvement beyond “wait and see”—experience headache reduction, cognitive fog lifting, mood stabilization, and functional recovery.

Chronic Traumatic Encephalopathy (CTE)

While CTE can only be definitively diagnosed post-mortem, patients with suspected CTE (multiple concussions, progressive symptoms, cognitive decline) report symptom improvement and slowed deterioration following ibogaine therapy.

Neuropathic Pain

Pain from nerve damage that opioids can’t touch without creating dependency. Fibromyalgia. Complex regional pain syndrome. Chronic pain driving addiction. Ibogaine’s NMDA receptor antagonism interrupts pain signaling at the source—offering relief that conventional treatments cannot provide.

The Neuroplasticity Factor

Medical training teaches that neurological damage is permanent. Ibogaine contradicts that dogma. The evidence base is growing but still limited by ibogaine’s legal status preventing large-scale trials. Clinical outcomes documented by providers like us consistently show improvement that shouldn’t be possible according to conventional neurology.

Treatment-Resistant Mental Health & Trauma

Accessing What Therapy Cannot Reach

Traditional mental health treatment works for many people. For those it doesn’t help—patients who’ve tried multiple medications, years of therapy, and every recommended approach without relief—ibogaine offers a different path.

PTSD & Combat Trauma

Clinical trials show 60-88% reduction in PTSD symptoms following ibogaine therapy. Veterans with treatment-resistant combat trauma, first responders with cumulative stress, survivors of assault or abuse—patients who’ve exhausted VA resources and traditional trauma therapy report breakthrough that seemed impossible.

Treatment-Resistant Depression

When SSRIs, SNRIs, tricyclics, MAOIs, ketamine, and ECT haven’t worked—when years of therapy produce no improvement—ibogaine’s neurotransmitter reset creates changes that conventional antidepressants cannot achieve. Patients describe lifting of depression that’s persisted for decades.

Anxiety Rooted in Trauma

Surface-level anxiety management (breathing exercises, cognitive reframing, medication) doesn’t address trauma-based anxiety. Ibogaine allows patients to process the traumatic material driving their anxiety—material that conscious therapy often cannot access.

Complex Grief

Loss that therapy can’t resolve. Grief that’s become pathological. Mourning that’s stolen years of life. Ibogaine facilitates emotional processing that talk therapy reaches only intellectually—allowing patients to actually feel, process, and begin releasing what they’ve carried.

Why It Works Differently

Ibogaine creates a unique psychological state where deeply buried memories, traumas, and patterns surface for processing. It’s not talk therapy—it’s direct access to subconscious material, allowing patients to confront and process what’s been driving symptoms for years or decades.

What Patients Report

Clarity about trauma origins. Emotional release that feels complete rather than temporary. Reduced hypervigilance. Improved sleep. Ability to connect with others. Freedom from symptoms that defined their existence.

Who Should Not Use 5-MeO-DMT

Important Safety Information

5-MeO-DMT is a powerful entheogenic medicine that is not safe or appropriate for everyone. The following conditions create serious risks and disqualify patients from this therapy:

Psychiatric Contraindications

ACTIVE PSYCHOSIS OR SCHIZOPHRENIA

Current psychotic symptoms or diagnosed schizophrenia spectrum disorders create extreme risk of psychological destabilization, prolonged psychotic episodes, or permanent worsening of condition. Even if currently stable on medication, the intensity of 5-MeO-DMT can trigger acute psychotic breaks.

SEVERE BIPOLAR DISORDER (TYPE I)

Particularly during manic or mixed episodes. 5-MeO-DMT can trigger manic episodes, destabilize mood regulation, or cause rapid cycling that’s difficult to manage medically.

SEVERE DISSOCIATIVE DISORDERS

Conditions like Dissociative Identity Disorder (DID) or severe depersonalization/derealization disorder may be dangerously exacerbated by ego-dissolving experiences.

ACTIVE SUICIDAL IDEATION WITH INTENT

While we treat depression and suicidal thinking with ibogaine, active intent to self-harm combined with 5-MeO-DMT’s intensity creates unacceptable risk during the vulnerable post-experience period.

Cardiovascular Contraindications

UNCONTROLLED HYPERTENSION

5-MeO-DMT can temporarily elevate blood pressure and heart rate. Uncontrolled high blood pressure (systolic >160, diastolic >100) creates stroke or cardiac event risk.

RECENT HEART ATTACK OR STROKE

Within 6 months. Cardiovascular system needs complete stabilization before additional stress from powerful medicines.

SEVERE CARDIAC ARRHYTHMIAS

Irregular heart rhythms that aren’t medically controlled create risk of dangerous cardiac events during the intense physiological response to 5-MeO-DMT.

ADVANCED HEART FAILURE

Compromised cardiac function cannot safely handle the temporary cardiovascular stress of the experience.

Medication Contraindications

MAOIs (Monoamine Oxidase Inhibitors)

Dangerous interaction. Must be discontinued with physician guidance well before 5-MeO-DMT.

SSRIs/SNRIs (Antidepressants)

Can create dangerous serotonin syndrome when combined with 5-MeO-DMT. Requires tapering and clearance period.

Lithium

Severe interaction risk. Creates potential for seizures and extreme psychological reactions.

Certain Blood Pressure Medications

Some interact dangerously. Full medication review required.

Other Contraindications

Pregnancy or Breastfeeding

Unknown risks to fetal development and infant exposure through breast milk. Absolutely contraindicated.

Severe Liver or Kidney Disease

Compromised organ function affects medicine metabolism and increases complication risk.

Seizure Disorders (Uncontrolled)

5-MeO-DMT can lower seizure threshold in susceptible individuals.

Recent Ibogaine Treatment Without Clearance

Must be medically stable and cleared by physicians. Timing matters for safety.

Psychological Readiness Concerns

Even if medically cleared, 5-MeO-DMT may not be appropriate if you:

Fear Losing Control

Ego dissolution means complete surrender. If the concept terrifies rather than intrigues you, this isn’t the right medicine.

Expect Recreational Experience

This is profound therapeutic work, not entertainment. Wrong expectations create difficult experiences.

Have Unrealistic Expectations

5-MeO-DMT is not a magic cure. It’s a tool for deep work that requires integration and effort.

Lack Integration Support

The experience demands processing. Without willingness to do integration work, benefits are lost.

Comprehensive Screening Required

Before any patient is approved for 5-MeO-DMT therapy, our physicians conduct:

Complete medical history review
Psychiatric evaluation
Medication interaction assessment
Cardiovascular screening
Psychological readiness evaluation
Informed consent discussion of all risks

We err on the side of caution. If there’s any question about safety, we decline to provide this therapy.

When in Doubt, We Say No

Your safety matters more than providing a requested service. If our medical team determines 5-MeO-DMT isn’t appropriate for you—even if you’ve traveled for ibogaine treatment—we won’t proceed.

This isn’t about excluding people. It’s about protecting lives.

Still Have Questions ? Talk to our Medical Team

Preparing for Treatment

What You'll Need to Do Before Arrival

Once you’re medically cleared for treatment, our Clinical Director will guide you through comprehensive preparation to ensure your body and mind are optimized for healing. Here’s what the preparation process involves:

Medical Preparation

COMPLETE REQUIRED SCREENING

Before traveling, you’ll need to complete and upload:

Echocardiogram – Provides detailed imaging of heart structure and function
Liver function panel – Evaluates your body’s ability to metabolize ibogaine safely
Additional tests as needed – Based on your medical history and condition

These allow our physicians to confirm eligibility and design your personalized protocol.

MEDICATION ADJUSTMENTS

Certain medications interact dangerously with ibogaine:

Antidepressants (SSRIs, SNRIs, MAOIs)
Benzodiazepines (Xanax, Klonopin, Valium)
Antipsychotics
Stimulants (Adderall, Ritalin, cocaine, methamphetamine)
Opioids (depending on your program)

CRITICAL: Never stop medications on your own. Our medical team provides individualized tapering schedules when clinically necessary. Some medications require weeks or months to safely discontinue.

Dietary Preparations

TWO WEEKS BEFORE ARRIVAL

Transition to clean, healing nutrition:

Reduce: Caffeine, processed foods, refined sugars, artificial additives
Increase: Whole foods, fresh vegetables, fruits, lean proteins, healthy fats
Focus: Simple, nutrient-dense meals that reduce inflammation and support healing

THREE DAYS BEFORE ARRIVAL

Enter strict dietary discipline:

Eliminate completely: Alcohol, recreational drugs, caffeine, non-prescribed substances
Avoid: Heavy, greasy, fried foods that stress digestion
Prioritize: Hydration (water, natural juices), light meals, easy digestion

DAY OF TREATMENT

You’ll fast (no food or liquids) for a designated period before ibogaine administration. Our medical team provides exact timing during your stay. Fasting optimizes absorption and reduces nausea risk.

WHY THIS MATTERS: Your diet directly impacts treatment safety and effectiveness. A clean system processes ibogaine more efficiently and reduces complications.

Physical Preparation

EXERCISE RECOMMENDATIONS

Encouraged: Walking, gentle yoga, stretching, light swimming
Avoid: Intense workouts, heavy weightlifting, exhausting cardio, competitive sports

Your body needs to be rested and balanced, not depleted.

SLEEP & RECOVERY

Prioritize 7-9 hours of quality sleep nightly in the week before treatment. A well-rested nervous system:

Supports neurological healing
Enhances therapeutic response
Reduces treatment complications
Improves integration capacity

HYDRATION PROTOCOL

Drink approximately 2 liters (8 cups) of water daily unless your physician directs otherwise. Proper hydration supports:

Electrolyte balance (critical for cardiac safety)
Metabolic function
Toxin elimination
Overall treatment efficacy

Mental & Emotional Preparation

SET YOUR INTENTION

Reflect deeply on why you’re seeking treatment. Journal about:

What am I ready to heal?
What patterns am I prepared to release?
What does freedom from my condition look like?
What do I hope to understand about myself?

Clear intention creates psychological focus and enhances therapeutic depth.

STRESS REDUCTION PRACTICES

Begin daily practices that calm your nervous system:

Meditation: Even 10-15 minutes daily
Journaling: Process fears, hopes, emotions
Breathwork: Box breathing, 4-7-8 technique
Prayer or spiritual practice: If meaningful to you

Reduced baseline stress increases your capacity for healing work.

BUILD YOUR SUPPORT NETWORK

Inform trusted family or friends about your journey:

Where you’ll be and when
What you’re seeking to heal
How they can support you after treatment
Your integration needs upon return

Post-treatment integration is significantly strengthened when you have understanding support at home.

Travel & Logistics

PASSPORT REQUIREMENTS

Your passport must be valid for at least 6 months beyond your travel dates. Mexican immigration strictly enforces this requirement.

WHAT TO PACK

Clothing:

Comfortable, loose-fitting clothes for treatment and recovery
Layers for varying comfort (facilities are climate-controlled)
Comfortable walking shoes

Essential Items:

Personal toiletries (we provide basics, but bring preferences)
Required medications in original labeled containers
Journal and writing materials
Books or reading for downtime
Personal comfort items (photos, spiritual objects, etc.)
Headphones if desired

WHAT NOT TO BRING

Expensive jewelry or valuables
Work laptops (this is healing time)
Recreational substances of any kind

What to Avoid Before Treatment

72 HOURS BEFORE ARRIVAL

Absolutely do not use:

Alcohol
Recreational drugs (cocaine, MDMA, cannabis, etc.)
Non-prescribed benzodiazepines or opioids
Stimulants
Any substance not approved by our medical team

Exception: If you’re in our Detoxification Program, opioid use before arrival is addressed through our stabilization protocol.

AVOID THESE ACTIVITIES

High-risk sports or dangerous activities
Physically exhausting work or exercise
Sudden dietary or medication changes without approval

WHY THIS MATTERS: These substances create dangerous interactions with ibogaine, compromise physical readiness, and can be life-threatening during treatment.

Personalized Guidance Every Step

Once you’re approved for treatment, our Clinical Director contacts you directly to provide:

Personalized nutritional recommendations based on your condition
Medication tapering schedule (if needed)
Travel coordination and arrival logistics
Answers to all your questions and concerns

You won’t navigate this alone. We guide you through every preparation step to ensure you arrive physically, mentally, and emotionally ready for transformative healing.

Questions about Preparation?

Our team is here to help you understand exactly what’s required, answer every question you have, and ensure you feel confident, informed, and fully prepared for the process ahead. You’re not expected to navigate this alone.